The amount of antibody produced by a person’s immune system can immediately correlate with the variety of gene copies encoding that particular antibody. This phenomenon, the place the quantity of protein expressed is proportional to the variety of gene copies, is noticed in a number of immunoglobulin sorts. An easy instance is seen in people with various numbers of sure IgG gene copies; these with extra copies are inclined to exhibit greater ranges of the corresponding IgG antibody of their serum.
The sensible relevance of this relationship extends to diagnostics and immunogenetics. Figuring out antibodies exhibiting such a correlation could be invaluable in figuring out genetic predispositions to sure illnesses or immune deficiencies. Traditionally, understanding gene copy quantity variation and its influence on protein expression has been basic in learning the genetic foundation of various phenotypic traits, together with immune responses.
